Tuesday, February 3, 2009

Cerebrolysin

Nootropic peptide drug. Hydrolysates brain substance containing amino acids. Used because of intramuscular and intravenous injections.
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Pharmacological Effects:
It promotes metabolism in brain tissue. Cerebrolysin contain biologically active amino acids and peptides, which are major parts of the cerebral metabolism. Penetrating through hematoencephalic barrier, the drug regulates intracellular exchange and enhances synaptic transmission. As a result of its introduction, increasing the efficiency of aerobic energy metabolism, improves intracellular protein synthesis, reduces the negative impact lactic acid intoxication. This effect, coupled with stimulation transsinaptic transfer provides neuroprotective effect of the drug, ie, increases the survival of neurons under conditions of hypoxia and other damaging effects.
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Indications for use:
Chronic cerebrovascular insufficiency (discirculatory encephalopathy), ischemic stroke, traumatic brain injury (concussion, brain injury, condition after surgery on the brain), delayed mental development in children, disorders associated with attention deficit in children, dementia syndromes of different genesis (Alzheimer's disease, senile altsgeymerovskogo type, vascular - multiinfarkt form, mixed); endogenous depression resistant to antidepressants. Increases the effect of antidepressant drugs.
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In psychiatry cerebrolysin successfully applied in psihoorganic syndrome. A 5-10 ml of intravenous jet. The treatment consists of 20-25 injections. Appointment of one of the most effective measures of compensation defect of mental activity in dementia of different genesis. Drip intravenous injection of 10-20 ml 100-250 ml of isotonic solution of sodium chloride (treatment - injections 20-30) reached a temporary reversal of memory and attention on improving the daily life activity. Therefore, the appointment of dementia showed repeated courses of treatment cerebrolysin.
For children with intellectual disabilities drug appoint intramuscularly at 1-2 mL daily for a month. Similar courses can be repeated 2-3 times a year. When Moderate mental defect is preferable to use it.
In endogenous depression resistant to antidepressants, improvement of the patients is usually 10-15 after intravenous (5 ml). After the sessions, and Electro-insulin-shock therapy mental activity of the patients recovered after 3-5 intravenous drip product introductions 10-15 mL in 100-250 ml of isotonic solution of sodium chloride.

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